62 Chapter 3 Late onset sepsis was definedas sepsis occurring72 hours after birthwithapositive blood culture or clinical signs of sepsis and relevant antimicrobial treatment (Dong 2015). Dong Y, Speer CP. Late-onset neonatal sepsis: recent developments. Arch Dis Child Fetal Neonatal Ed 2015;100(3):F257-F63. doi: 10.1136/archdischild-2014-306213 [published Online First: 2014/11/25] Intraventricular hemorrhage and post hemorrhagic ventricle dilatation were defined according to Papile (Papile 1978). I. Grade 1: subependymal hemorrhage II. Grade 2: intraventricular hemorrhage without ventricular dilatation III. Grade 3: intraventricular hemorrhage with ventricular dilation IV. Grade 4: intraventricular hemorrhage with parenchymal hemorrhage Papile LA, Burstein J, Burstein R, et al. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 1978;92(4):529-34. doi: 10.1016/s0022-3476(78)80282-0 [published Online First: 1978/04/01] Retinopathy of prematurity was defined according to the 2005 International Classification of Retinopathy of Prematurity I. Stage I: Demarcation line II. Stage 2: Ridge III. Stage 3: Extraretinal fibrovascular proliferation, i.e. neovascularization from the ridge into the vitreous IV. Stage 4: Partial retinal detachment International Committee for the Classification of Retinopathy of P. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol 2005;123(7):991-9. doi: 10.1001/archopht.123.7.991 [published Online First: 2005/07/13] Infant respiratory distress syndrome was gradedaccording toGiedion (Giedion 1973). I. Grade 1: Reticulogranular pattern II. Grade 2: Reticulogranular patterin and air bronchogram III. Grade 3: Reticulogranular pattern, air bronchogram and loss of distinct heart borders IV. Grade 4: Diffuse opacification and obscuration of the cardiac silhouette Giedion A, Haefliger H, Dangel P. Acute pulmonary X-ray changes in hyaline membrane disease treated with artificial ventilation and positive end-expiratory pressure (PEP). Pediatr Radiol 1973;1(3):145-52. doi: 10.1007/BF00974058 [published Online First: 1973/10/01]
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