122 model ANOVA was performed with attenuation group as the betweensubjects factor with two levels (counterconditioning, extinction) and the nocebo reduction as the within-subjects factor with 2 levels (first nocebo trial of the first evocation phase pre-attenuation, first nocebo trial of the second evocation phase post-attenuation). Resistance to extinction To test the hypothesis that conditioning with partial reinforcement would lead to a more durable nocebo effect as compared to conditioning with continuous reinforcement, we explored resistance to extinction. A 2x2 mixed model ANOVA was performed with the induction group as between-subjects factor with two levels (partial reinforcementextinction, continuous reinforcement-extinction) and the nocebo response as the within-subjects factor with 2 levels (first nocebo trial of the first evocation phase pre-attenuation, first nocebo trial of the second evocation phase post-attenuation). Following this, two repeated measures ANOVAs were conducted with the nocebo response as the within-subjects factor with 2 levels (as described above), to test whether extinction significantly reduced the magnitude of nocebo hyperalgesia within the partial reinforcement group and within the continuous reinforcement group. Manipulation-check for the time-course of extinction Because of the unique attenuation paradigm in the experiment, we implemented a design that applied 10 evocation trials, that were essentially extinction trials, before the start of the 30 attenuation trials. In our paradigm, 30 induction trials were followed by 10 evocation trials, which in turn were followed by 30 extinction trials. Evocation trials,
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