70 component, related to processing of imminent pain. trials linked to lower amplitudes Tu 2019 21 Conditioning & Observational learning Thermal 20 trials in direct conditioning (2-second plateau) MEG Resting-state MEG, pre- and post- the nocebo manipulation Decreased alpha connectivity between the left rostral anterior cingulate cortex and left middle temporal gyrus Benedet ti 2006 37 NVS Ischemic n/a Pharmaco logy Pharmacologica l manipulations and measurement of adrenocorticotr opic hormone and cortisol plasma concentrations Increased adrenocortic otropic hormone and cortisol plasma concentratio ns Benedet ti 2014 35 Socially induced NVS Hypoxiainduced headache n/a Biochemi cal Pharmacologica l manipulations and measurement of Salivary PG, TXA2, and cortisol Prostaglandi n, thromboxane A2, and salivary cortisol increases Scott 2008 5 NVS Needle puncture s n/a PET Measurement of μ-opioid and dopamine (D2/D3 receptor) neurotransmissi on Deactivation of μ-opioid and mesolimbic dopamine neurotransmi ssion Egorova 2015 30 Conditioning & Nonconscious evocation Thermal 22 trials in conditioning (4-second plateau) tDCS Manipulation of brain activity via electrical currents that increase and decrease neuronal excitability in the DLPFC Involvement of dorsolateral prefrontal cortex activation Keltner 2006 13 Conditioning Thermal 5 trials in precondition ing 10 trials in conditioning (30-second plateau) fMRI Differences in BOLD activations Increased activation in caudal anterior cingulate cortex and cerebellum, and thalamic levels
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