231 OPERAM: cluster randomised controlled trial Table 1. Baseline characteristics of clusters and patients. Control Intervention CLUSTERS, N 56 54 Cluster size 16.0 (11.8 - 25.2) 16.5 (10.0 - 23.8) Cluster specialty type Medical 42 (75%) 43 (80%) Surgical 14 (25%) 11 (20%) Time between first and last recruitment, weeks 24.6 (15.2 - 37.3) 23.9 (11 - 35.9) PATIENTS, N 1,045 963 Cluster specialty type 1 Medical 825 (78.9%) 764 (79.3%) Surgical 220 (21.1%) 199 (20.7%) Age, years 79 (74 - 84) 79 (74 - 84) < 80 years 557 (53%) 521 (54%) ≥ 80 years 488 (47%) 442 (46%) Female 453 (43%) 445 (46%) Trial site Bern, Switzerland 376 (36%) 446 (46%) Cork, Ireland 208 (20%) 138 (14%) Louvain, Belgium 238 (23%) 150 (16%) Utrecht, The Netherlands 223 (21%) 229 (24%) Number of comorbidities 10 (8 - 15) 11 (8 - 16) Number of medications 9 (7 - 12) 10 (7 - 13) Non-independently living 2 216 (21%) 168 (17%) Dementia 49 (5%) 51 (5%) Any fall during the last year 405 (39%) 364 (38%) Number of falls during the last year 0 (0 - 1) 0 (0 - 1) Any hospitalization during the last year 533 (51%) 486 (51%) Number of hospitalizations during the last year 1 (0 - 1) 1 (0 - 1) BMI, kg/m2 26.5 (23.7 - 30.1) 26 (23.2 - 29.6) Current smoking 81 (8%) 77 (8%) EQ-5D VAS 3 60 (45 - 72) 60 (50 - 73) Pain/discomfort score (EQ-5D) 4 1 (0 - 2.00) 1 (0 - 2.00) Barthel Index of ADL 5 90 (80 - 100) 95 (75 - 100) ©MMAS-8 6 7 (6 - 7) 7 (6 - 7) Length of stay during index hospitalization 9 (6 - 14) 8 (6 - 13) Cluster and patient characteristics are presented as number and percentage (based on all -missing and non-missing- data) or median and interquartile range for categorical and continuous variables, respectively. Missing data: Number of comorbidities at baseline: 3 (0.1%); number of medication at baseline: 3 (0.1%); number of falls during the last year: 19 (0.9%); number of hospitalizations during the last year: 12 (0.6%); BMI: 163 (8.1%); EQ5D VAS: 92 (4.6%); pain/discomfort score (EQ-5D) at baseline: 20 (1%); Barthel Index of ADL at baseline: 45 (2.2%); ©MMAS-8 at baseline: 99 (4.9%); Length of stay during index hospitalization: 28 (1.4%). 3
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