243 OPERAM: cluster randomised controlled trial Conclusion In this cluster-RCT of older multimorbid patients with polypharmacywhowere admitted to hospital, a mean of 2.75 STOPP/START recommendations per patient were provided in the intervention group and 62% of patients had ≥1 recommendation implemented at 2 months, mostly discontinuation of inappropriate medication. Drug-related hospital admissions were not significantly reduced in the intervention group compared to the control group despite providing evidence-based recommendations to physicians and patients. However, the intervention caused no detriment to patient outcomes. 3
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