251 OPERAM: cluster randomised controlled trial - SI SUPPLEMENTARY INFORMATION SI SI1 - Figures and tables Figure SI1.1 Cluster flow chart Figure SI1.2 Time to first drug-related hospital admission Figure SI1.3 Per-protocol analysis for time to first drug-related hospital admission Figure SI1.4 Subgroup analysis for first drug-related hospital admission Figure SI1.5 Kaplan-Meier curve for all-cause death Figure SI1.6 Subgroup analysis for all-cause death Table SI1.1 Baseline medications grouped by ATC drug class and study group Table SI1.2 I nvolved or omitted medication classes in adjudicated drug-related hospital admissions Table SI1.3 Per protocol analysis for time to first event outcomes Table SI1.4 T ime-to-event analysis taking into account competing risks (regression on sub-hazards) Table SI1.5 Analysis adjusted for baseline characteristics Table SI1.6 Variation of the intervention effect across time Table SI1.7 P atient-reported outcomes, considering only interviews within the pre-specified time window Table SI1.8 Intracluster correlation for main outcomes SI2 - Methods appendix - STRIPA - Structured History of Medication (SHiM) - Definations of underuse, overuse and misuse in Table 5 References supplementary information 3
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