262 CHAPTER 3.2 Table SI1.6. Variation of the intervention effect across time. Outcome N HR (95% CI) 1 P value P for interaction First drug-related hospital admission Before 2 months 2,008 0.98 (0.70 to 1.37) 0.91 0.80 After 2 months 1,685 0.93 (0.73 to 1.19) 0.57 Death by cancer Before 2 months 2,008 0.71 (0.35 to 1.46) 0.35 0.82 After 2 months 1,822 0.79 (0.47 to 1.33) 0.38 First hospitalization Before 2 months 2,008 0.91 (0.74 to 1.11) 0.34 0.76 After 2 months 1,454 0.86 (0.71 to 1.03) 0.11 First fall Before 2 months 2,008 0.98 (0.72 to 1.33) 0.89 0.86 After 2 months 1,660 0.94 (0.76 to 1.18) 0.61 Death Before 2 months 2,008 0.93 (0.64 to 1.35) 0.71 0.88 After 2 months 1,822 0.88 (0.68 to 1.14) 0.33 1 HR<1 indicates less events in the intervention group. Abbreviations: CI, confidence interval; HR, hazard ratio; N, number
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