365 Detectability of medication errors in older people prior to potentially preventable admissions Time to first potentially preventable DRA Of 72 first potentially preventable DRAs, 33.3% (n = 24) occurred in the period between discharge and 2 months, whereas 29.2% (n = 21) occurred 2–6 months after the in-hospital medication review and 37.5% (n = 27) occurred 6–12 months after the in-hospital medication review. The cumulative incidence of MEs over time stratified for present and not present MEs during the in-hospital medication review is shown in Figure 4. No clear time relationship was observed between the occurrence of a potentially preventable DRA and the presence of MEs during the in-hospital medication review. Figure 4. Cumulative incidence (%) of MEs over time stratified for total, present, and not present MEs during the in-hospital medication review. Discussion Main findings About half of MEs (48%) were not present during an in-hospital medication review in the year prior to potentially preventable DRA and were therefore not detectable at that time. Of the MEs that were present during the in-hospital medication review, 60% were detected by CDSS-generated STOPP/START signals, however, only about half of these signals (54%) were considered clinically applicable and resulted in a recommendation. Overall, the pharmacotherapy teams recommended a change in medication regimen in 50% of present MEs; however, these proposed recommendations were not implemented. Underuse was the most frequently identified ME type (49%), followed by overuse (36%) and misuse (14%) of drugs. 4
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