370 CHAPTER 4.3 Declarations Authors’ contributions Authorship eligibility is based on the ICMJE authorship criteria. The authors certify that they have participated in the aspects of conception and design (BS, CH, TE, EvP, IW, WK), acquisition and interpretation of data (all authors), drafting the article (BS, JI, TE, EvP, IW, WK) and revising it critically for important intellectual content (all authors). All authors have approved the final article. Competing interests The author(s) declare that they have no competing interests. Data availability statement Data for this study will be made available to others in the scientific community upon request after publication. Data will be made available for scientific purposes for researchers whose proposed use of the data has been approved by a publication committee. Ethics approval The OPERAM trial was approved by the independent research ethics committees at each participating site (lead ethics committee: Cantonal Ethics Committee Bern, Switzerland, ID 2016-01200; Medical Research Ethics Committee Utrecht, Netherlands, ID 15-522/D; Comité d’Ethique Hospitalo-Facultaire Saint-LucUCL: 2016/20JUL/347–Belgian registration No: B403201629175; Cork University Teaching Hospitals Clinical Ethics Committee, Cork, Republic of Ireland; ID ECM 4 (o) 07/02/17), and Swissmedic as responsible regulatory authority. Funding This work is part of the project “OPERAM: OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly” supported by the European Union's Horizon 2020 research and innovation program under the grant agreement No 634238, and by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 15.0137. The OPERAM-project was also partially funded by the Swiss National Science Foundation (SNSF 320030_188549). The work of Katharina Tabea Jungo was supported by the Swiss National Science Foundation (SNSF), grant No NFP74 407440_167465. The opinions expressed herein are those of the authors and do not necessarily reflect the official views of the European
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