Bastiaan Sallevelt

Chapter 1 General Introduction	9
Chapter 2 Applicability of tools for medication optimisation in hospitalised older people	31
2.1 Performance of a trigger tool for detecting adverse drug reactions in patients with polypharmacy acutely admitted to the geriatric ward	33
2.2 Evaluation of clarity of the STOPP/START criteria for clinical applicability in prescribing for older people: A quality appraisal study	59
2.3 Conversion of STOPP/START version 2 into coded algorithms for software implementation: A multidisciplinary consensus procedure	111
Chapter 3 Process development and clinical outcomes of in-hospital medication reviews	193
3.1 Intervention protocol: OPtimising thERapy to prevent avoidable hospital Admission in the Multi-morbid elderly (OPERAM): a structured medication review with support of a computerised decision support system	195
3.2 Optimizing therapy to prevent avoidable hospital admissions in multimorbid older adults (OPERAM): cluster randomised controlled trial	219
Chapter 4 Evaluation of the in-hospital medication review process	273
4.1 Frequency and acceptance of clinical decision support systemgenerated STOPP/START signals for hospitalised older patients with polypharmacy and multimorbidity	275
4.2 Hospital physicians' and older patients' agreement with individualised STOPP/START-based medication optimisation recommendations in a clinical trial setting	325
4.3 Detectability of medication errors with a STOPP/START-based medication review in older people in the year prior to a potentially preventable drug-related admission	349
Chapter 5 General Discussion	389
Chapter 6 Summary	427
Chapter 7 Nederlandse samenvatting	435
Chapter 8 Appendices	447
Chapter 9 Dankwoord	459

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