Effects of magnesium citrate, magnesium oxide and magnesium sulfate on arterial stiffness 123 6 Magnesium citrate (n=46) Magnesium oxide (n =46) Magnesium sulfate (n =46) Placebo (n =26) 12-wk Mean, % 25.3 ± 8.4 20.8 ± 9.0 23.3 ± 9.1 21.5 ± 10.0 Difference vs placebo 0.7 (-1.7; 3.0) 0.1 (-2.2; 2.5) 0.7 (-1.6; 3.0) . . 24-wk Mean, % 24.7 ± 8.9 21.3 ± 8.3 23.9 ± 9.1 22.4 ± 10.4 Difference vs placebo -1.0 (-3.3; 1.4) -0.1 (-2.5; 2.2) 0.5 (-1.8; 2.8) . . Values are mean ± SD. Adjusted mean differences (95% CIs) were obtained from linear mixedeffect models with age, sex, baseline value of the outcome of interest, time, intervention, and the interaction time × intervention as fixed effects. c-fPWV; carotid-to-femoral pulse wave velocity, AI@HR75; augmentation index adjusted for heart rate. Table 3. Effects of magnesium citrate, magnesium oxide and magnesium sulfate (vs placebo) on blood pressure. Magnesium citrate (n =46) Magnesium oxide (n =46) Magnesium sulfate (n =46) Placebo (n =26) Systolic blood pressure 2-wk Mean, mm Hg 131 ± 14 127 ± 15 130 ± 15 130 ± 15 Difference vs placebo -1 (-5; 2) -0 (-4; 3) 0 (-4; 4) . . 12-wk Mean, mm Hg 132 ± 15 125 ± 14 129 ± 13 127 ± 13 Difference vs placebo 2 (-2; 6) 1 (-3; 5) 2 (-2; 5) . . 24-wk Mean, mm Hg 133 ± 16 127 ± 15 131 ± 16 129 ± 13 Difference vs placebo 1 (-2; 5) 1 (-2; 5) 2 (-2; 6) . . Diastolic blood pressure 2-wk Mean, mm Hg 78 ± 8 77 ± 8 79 ± 8 80 ± 8 Difference vs placebo -1 (-3; 1) -1 (-3; 1) -1 (-2; 1) . . 12-wk Mean, mm Hg 78 ± 9 75 ± 8 79 ± 8 80 ± 9 Difference vs placebo -1 (-3; 2) -1 (-4; 1) -1 (-3; 2) . . 24-wk Mean, mm Hg 79 ± 9 76 ± 9 79 ± 9 80 ± 9 Difference vs placebo 0 (-2; 2) -0 (-2; 2) -0 (-2; 2) . . Mean arterial pressure 2-wk Mean, mm Hg 96 ± 10 93 ± 10 96 ± 10 97 ± 10 Difference vs placebo -1 (-3; 1) 0 (-2; 2) -0 (-3; 2) . . Table 2. (Continued)
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