Chapter 6 146 Magnesium citrate (n=46) Magnesium oxide (n=46) Magnesium sulfate (n=46) Placebo (n=26) 12-wk Mean, mmol/24-h 135.7 ± 45.6 146.9 ± 51.2 159.8 ± 60.7 130.7 ± 41.6 Difference vs placebo 17.4 (-8.8; 43.5) 26.2 (0.3; 52.2)* 34.4 (8.8; 60.1)** .. 24-wk Mean, mmol/24-h 141.7 ± 45.5 153.0 ± 52.6 150.4 ± 57.4 131.2 ± 39.3 Difference vs placebo 21.9 (-4.5; 48.3) 30.5 (4.4; 56.5)* 23.7 (-2.2; 49.6) .. Urinary creatinine 2-wk Mean, 12.6 ± 3.5 12.7 ± 4.0 13.1 ± 4.2 12.6 ± 3.7 Difference vs placebo 0.2 (-1.2; 1.5) 0.3 (-1.1; 1.6) 0.3 (-1.1; 1.6) .. 12-wk Mean, 13.0 ± 3.6 12.9 ± 3.7 13.3 ± 4.0 12.6 ± 3.7 Difference vs placebo 0.5 (-0.8; 1.8) 0.6 (-0.8; 1.9) 0.5 (-0.8; 1.9) .. 24-wk Mean, 12.6 ± 3.2 13.0 ± 3.8 12.7 ± 3.3 12.6 ± 3.5 Difference vs placebo 0.1 (-1.3; 1.4) 0.7 (-0.6; 2.0) -0.1 (-1.4; 1.3) .. Values are mean ± SD. Adjusted mean differences (95% CIs) were obtained from linear mixedeffect models with age, sex, baseline value of the outcome of interest, time, intervention, and the interaction time × intervention as fixed effects. * P < 0.05, ** P<0.01 (two-sided P values). Supplemental Table 4. Effects of magnesium citrate, magnesium oxide and magnesium sulfate (vs placebo) on body composition. Magnesium citrate (n=46) Magnesium oxide (n=46) Magnesium sulfate (n=46) Placebo (n=26) Weight 2-wk Mean, kg 85.7 ± 12.9 82.8 ± 12.0 86.0 ± 11.8 85.5 ± 10.4 Difference vs placebo -0.1 (-0.8; 0.6) 0.0 (-0.7; 0.8) -0.2 (-0.9; 0.5) .. 12-wk Mean, kg 86.6 ± 12.1 83.0 ± 12.0 86.3 ± 12.0 86.1 ± 9.8 Difference vs placebo -0.1 (-0.8; 0.7) 0.2 (-0.6; 0.9) 0.3 (-0.4; 1.0) .. 24-wk Mean, kg 86.3 ± 12.7 82.6 ± 12.0 86.5 ± 12.6 85.9 ± 9.8 Difference vs placebo 0.0 (-0.8; 0.7) 0.3 (-0.4; 1.0) 0.7 (-0.0; 1.4) .. BMI 2-wk Mean, kg/m2 28.6 ± 3.4 27.5 ± 2.1 28.3 ± 2.8 27.8 ± 2.5 Difference vs placebo -0.0 (-0.3; 0.2) 0.0 (-0.2; 0.3) -0.1 (-0.3; 0.2) .. 12-wk Mean, kg/m2 28.7 ± 3.4 27.5 ± 2.1 28.5 ± 2.9 27.6 ± 2.5 Difference vs placebo -0.0 (-0.3; 0.2) 0.1 (-0.2; 0.3) 0.1 (-0.1; 0.3) .. Supplemental Table 3. (Continued)
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