Chapter 3 72 Supplemental Table 2. Linear regression analyses with 24-h urinary magnesium excretion as dependent variable, stratified for age and sex1. Urinary magnesium excretion, mmol/24-h Determinant Univariate St. β (95% CI) Multivariate St. β (95% CI) Body mass index, kg/m2 Age < 55 -0.02 (-0.08; 0.05) -0.04 (-0.11; 0.02) Age ≥ 55 -0.11 (-0.19; -0.03)* -0.09 (-0.17; -0.02)* Waist circumference, cm Males -0.03 (-0.12; 0.07) -0.06 (-0.25; 0.13) Females -0.13 (-0.19; -0.07)** -0.10 (-0.21; 0.02) Age < 55 0.05 (-0.01; 0.12) -0.06 (-0.13; 0.01) Age ≥ 55 -0.04 (-0.13; 0.04) -0.12 (-0.21; -0.04)* LDL cholesterol, mmol/L Males 0.10 (0.02; 0.18)* 0.10 (0.02; 0.18)* Females -0.02 (-0.08; 0.04) 0.003 (-0.06; 0.07) Age < 55 0.04 (-0.03; 0.10) -0.02 (-0.09; 0.05) Age ≥ 55 0.06 (-0.03; 0.14) 0.09 (0.01; 0.16)* Systolic BP, mm Hg Males 0.06 (-0.04; 0.15) 0.09 (-0.01; 0.20) Females -0.07 (-0.12; -0.01)* -0.04 (-0.10; 0.03) Age < 55 0.08 (0.01; 0.16)* 0.02 (-0.07; 0.10) Age ≥ 55 0.01 (-0.07; 0.09) 0.04 (-0.04; 0.12) eGFR < 90 ml/min/1.73m2 Age < 55 -0.10 (-0.28; 0.07) -0.09 (-0.27; 0.08) Age ≥ 55 -0.31 (-0.48; -0.14)** -0.25 (-0.43; -0.08)* Creatinine clearance, mL/min Males 0.43 (0.35; 0.50)** 0.51 (0.43; 0.59)** Females 0.43 (0.37; 0.50)** 0.54 (0.47; 0.61)** Plasma potassium, mmol/L Age < 55 0.14 (0.08; 0.21)** 0.10 (0.03; 0.16)* Age ≥ 55 -0.02 (-0.10; 0.06) -0.01 (-0.09; 0.07) MCV, fL Males -0.10 (-0.19; -0.02)* -0.09 (-0.18; -0.01)* Females 0.04 (-0.02; 0.10) 0.04 (-0.02; 0.10) 1Associations presented in this table were significantlymodified by age and/or sex (all associations: Pinteraction <0.1). Multivariable models were adjusted for age, sex, BMI, eGFR (< 90 ml/min/1.73m2), plasma sodium and plasma potassium, and smoking and alcohol consumption. Abbreviations: eGFR, estimated glomerular filtration rate; MCV, mean corpuscular volume,*p <0.05, **p <0.001
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