Zainab Assy

122 Chapter 6 Table 2: The salivary film thickness at five intra-oral location, stratified according to sex. N indicates the number of participants in each group. Data are presented as median with corresponding interquartile range (IQR). Intra-oral loacations Salivary film thickness in µm (N=40) Median ± IQR Female salivary film thickness in µm (N=18) Median ± IQR Male salivary film thickness in µm (N=22) Median ± IQR Anterior part of the tongue 68.9 ± 57.6-77.4 65.2 ± 57.4-73.4 74.0 ± 59.4-79.3 Anterior part of the palate 11.3 ± 5.2-19.1a 6.0 ± 4.1-13.8** 15.7 ± 9.2-22.0 Posterior part of the palate 29.7 ± 17.4-44.3a,b 28.0 ± 15.7-39.0 31.4 ± 21.1-53.3 Inside cheeks 44.0 ± 34.8-58.5a,b,c 40.0 ± 27.1-50.0** 55.4 ± 39.7-68.5 Floor of the mouth 62.5 ± 46.3-78.7a,b,c,d 52.5 ± 33.5-78.9 67.4 ± 54.4-78.6 ** Female vs. male difference Mann-Whitney U test p-value <0.01 a Wilcoxon signed-rank tests: p < 0.05 vs. anterior part of the tongue b Wilcoxon signed-rank tests: p < 0.05 vs. anterior part of the palate c Wilcoxon signed-rank tests: p < 0.05 vs. posterior part of the palate d Wilcoxon signed-rank tests: p < 0.05 vs. inside cheeks Table 3: The MUC5B levels at five intra-oral locations, stratified according to sex. N indicates the number of participants in each group. Data are presented as median with corresponding interquartile range (IQR). Intra-oral locations MUC5B in AU/mL (N=34)# Median ± IQR Female MUC5B in AU/mL (N=16)# Median ± IQR Male MUC5B in AU/mL (N=18)# Median ± IQR Anterior part of the tongue 0.127 ± 0.040-0.353 0.089 ± 0.037-0.173 0.273 ± 0.040-0.638 Anterior part of the palate 0.003 ± 0.000-0.011a 0.000 ± 0.000-0.003* 0.006 ± 0.000-0.017 Posterior part of the palate 0.020 ± 0.009-0.121a,b 0.018 ± 0.005-0.039 0.027 ± 0.012-0.208 Inside cheeks 0.008 ± 0.000-0.034a,b 0.008 ± 0.000-0.032 0.010 ± 0.000-0.075 Floor of the mouth 0.007 ± 0.000-0.029a,b,c 0.002 ± 0.000-0.030 0.012 ± 0.000-0.029 * Female vs. male difference Mann-Whitney U test p-value <0.05 a Wilcoxon signed-rank tests: p < 0.05 vs. anterior part of the tongue b Wilcoxon signed-rank tests: p < 0.05 vs. anterior part of the palate c Wilcoxon signed-rank tests: p < 0.05 vs. posterior part of the palate # The total number differs as MUC5B samples were not available for all participants.

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