144 Chapter 7 Table 2: Perceived oral dryness in four different intra-oral regions of the upper jaw as determined with the Regional Oral Dryness Inventory (RODI) in six different patient groups. Data are presented as median with corresponding interquartile range (IQR) and as a mean with standard deviation (SD.). N indicates the total number of subjects per intra-oral region. Patient groups Upper lip: mean±SD. (N)* Upper lip: median±IQR Anterior palate: mean±SD. (N)* Anterior palate: median±IQR Posterior palate: mean±SD. (N)* Posterior palate: median±IQR Inside cheeks: mean±SD. (N)* Inside cheeks: median±IQR Controls# (N=136) 2.40±1.31 (N=113) 2.00±1.00-3.00 2.34±1.25 (N=114) 2.00±1.00-3.00 2.64±1.23 (N=115) 3.00±1.00-4.00 2.05±1.25 (N=113) 1.00±1.00-3.00 Low Med patients (N=157) 2.68±1.21 (N=134) 3.00±2.00-4.00 2.74±1.26 (N=131)a 3.00±2.00-4.00 2.81±1.32 (N=135) 3.00±1.00-4.00 2.28±1.30 (N=130) 2.00±1.00-3.00 High Med patients (N=140) 3.08±1.28 (N=121)a,b 3.00±2.00-4.00 3.23±1.35 (N=119)a,b 4.00±2.00-4.00 3.23±1.32 (N=122)a,b 4.00±2.00-4.00 2.78±1.34 (N=121)a,b 3.00±2.00-4.00 RTX patients (N=10) 3.00±1.05 (N=10) 3.00±2.00-4.00 3.00±1.00 (N=9) 3.00±2.50-4.00 3.30±1.42 (N=10) 4.00±1.75-4.00 3.30±0.82 (N=10)a,b 3.50±2.75-4.00 SS patients (N=46) 3.40±0.98 (N=40)a,b 3.00±3.00-4.00 3.33±1.14 (N=40)a,b 4.00±3.00-4.00 3.79±0.90 (N=42)a,b,c 4.00±3.00-4.00 2.98±1.07 (N=40)a,b 3.00±2.00-4.00 SS + High Med patients (N=22) 3.50±1.04 (N=18)a,b 4.00±2.75-4.00 3.72±0.75 (N=18)a,b 4.00±3.00-4.00 3.84±0.50 (N=19)a,b 4.00±4.00-4.00 3.42±1.07 (N=19)a,b,c 4.00±3.00-4.00 # controls: subjects visiting a saliva clinic who did not use prescription medication, were not treated with radiotherapy in head and/or neck region and were not diagnosed with Sjögren’s syndrome. * Indicates significant differences between the six patient groups; Kruskal Wallis test p<0.01. Mann-Whitney U test: a p<0.05 vs. controls, b p<0.05 vs. Low Med patients, c p<0.05 vs. High Med patients, d p<0.05 vs. RTX patients, and e p<0.05 vs. SS patients. Reprinted with permission from Clinical Oral Investigations 2021;25:4031–4043
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