Chapter 2 ABSTRACT Objectives Several questionnaires, such as the internationally validated and frequently used Xerostomia Inventory (XI), havebeendeveloped toquantify the subjective feelingof adrymouth. Thesequestionnaires quantify theoverall perceptionof drymouthbut lack the possibility to differentiate between various intra-oral regions. In this light, a novel questionnaire, theRegional Oral Dryness Inventory (RODI), whichquantifies the severity of dryness at various locations in themouth, was evaluated. Material andmethod A retrospective case report studywas designed. Datawere collected frompatients who visited the salivaclinic for Special CareDentistry inAmsterdam. Data, including the saliva secretion rates, RODI scores, the Xerostomia Inventory (XI) score, and Clinical Oral Dryness Score (CODS), wereextracted fromtheelectronichealth record systemOase Dental. Results A total of 337 patients participated in this study with an average age of 54 ± 17 years. The majority of the patients were female (68.5%). The perceived dryness as determinedby theRODIwas thehighest for theposteriorpalateand the lowest for the floor of themouth. Thehighest correlationswere foundbetween the corresponding regions in the RODI and regionally related individual items of the XI and CODS. Conclusion There isasignificant difference indry-mouth feelingat different intra-oral locations. Clinical relevance Regional evaluation of xerostomia with the RODI might improve diagnosis of xerostomia by helping to discriminate between different potential causes of oral dryness in patients and for evaluating the efficacy of mouth-moistening products. The RODI is highlyaccessibleandeasy toperformindental practices during routine clinical assessment. Keywords Drymouth, Xerostomia, Salivaryflowrate, Xerostomia Inventory, Clinical Oral Dryness Score 28
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