58 Chapter 3 Table 4: Patients were divided into six different patient groups based on their health status. Several patient characteristics for the six groups are shown; age, distribution of women and men in each group, the total number of medications used, the total XI-scores, salivary flow rates (in mL/min), and the salivary pH of UWS, CH-SWS, and A-SWS. The age is presented as mean with standard deviation (SD.) For the number of medications used, the total XI-scores, salivary flow rates, and salivary pH the median with corresponding interquartile range (IQR) is shown. The distribution of women and men is given in percentages. N indicates the total subjects for each patient group. Patient groups (N=517) N Age: mean±SD.* % of women: men* Number of medication: median±IQR * Total XI-scores: median±IQR* UWS: median±IQR* pH UWS: median±IQR CH-SWS: median±IQR* pH CH-SWS: median±IQR A-SWS: median±IQR* pH A-SWS: median±IQR* Controls 136 50.6±17.7 64.2: 35.8 - 27.0±19.034.0 0.22±0.070.36 6.50±6.107.00 0.76±0.441.33 7.00±6.707.00 1.62±1.012.20 4.70±4.405.80 Low Med patients 157 60.7±14.8a 68.2: 31.8 2±1-2a 30.0±22.037.0a 0.17±0.070.32 6.50±6.107.00 0.72±0.391.18 7.00±6.507.00 1.17±0.711.80a 4.70±4.006.10 High Med patients 140 65.9±13.1a,b 65.7: 34.3 6±4-9a,b 33.0±24.040.0a,b 0.11±0.040.30a,b 6.5±5.806.90 0.57±0.271.08a 7.00-6.107.00 0.95±0.441.50a,b 4.40±4.005.00a,b RTX patients 10 58.7±17.9 40.0: 60.0 1±0-1a,b,c 37.5±31.043.8a,b 0.13±0.050.23 6.10±5.656.90 0.45±0.290.76 7.00±6.407.00 0.52±0.240.95a,b 4.55±4.155.08 SS patients 46 61.7±14.0a 84.8: 15.2a,b,c,d 2±-2a,b,c,d 44.0±37.049.8a,b,c 0.08±0.030.16a,b 6.50±6.006.80 0.30±0.050.61a,b,c 6.90±6.107.00 0.50±0.231.15a,b,c 4.40±4.005.00a,b SS + High Med patients 22 62.1±9.1a 95.5: 4.5a,b,c,d 7±5-9a,b,d,e 46.0±37.5-49.5a,b,c,d 0.06±0.03w0.16a,b 6.50±5.50 -7.00 0.28±0.140.56a,b,c 7.00±6.50 -7.00 0.48±0.231.35a,b 4.40±4.004.70a,b * Indicates significant differences between the six patient groups, Kruskal Wallis test p<0.01. Mann-Whitney U test: a p<0.05 vs controls, b p<0.05 vs Low Med patients, c p<0.05 vs High Med patients, d p<0.05 vs RTX patients, and e p<0.05 vs SS patients.
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