86 Chapter 4 Statistical analysis For statistical analysis, SPSS version 25.0 (IBM Corp SPSS statistics, Armonk, NY, USA) was used. The intraclass correlation coefficient (ICC) was used to determine the degree of agreement between the anthropometric measurements and the oral surface areas. A two-way mixed, absolute agreement, average-measures ICC was calculated for the anthropometric measurements. To measure the agreements between the different researchers for the oral surface areas, a two-way random, absolute agreement, average measures ICC was used [14, 21]. The reliability index is indicative of poor (values less than 0.5), moderate (between 0.5 and 0.75), good (between 0.75 and 0.9) and excellent (greater than 0.90) reliability [20]. The mean of the two anthropometric measurements and the mean of different intra-oral surface areas were used for further analysis. The relationship between anthropometric measurements and the intra-oral surface area was analyzed by a Pearson correlation coefficient. The size of the correlation coefficient was interpreted as negligible (r = 0.1–0.2), fair (r = 0.3–0.5), moderate (r = 0.6–0.7) or very strong (r = 0.8–0.9) correlation [1]. An ANOVA one-way test was performed to check for significant differences between females and males. All significance levels (P) were set at 0.05. RESULTS Intra‑oral surface areas Using CBCT and digital analysis, it was possible to determine the intra-oral surface area. The median of the ICC for the intra-oral surface areas was 0.95 (Table 2). The resulting ICC for the different areas was good or excellent. The mean and standard deviation for the intra-oral surface areas, determined by CBCT and digital analysis, were calculated for the total cadavers, and females and males separately (Table 2). The mean intra-oral surface area of all the included cadavers was 173.3 ± 19.3 cm2. ANOVA testing found no significant differences in mean surface areas of the four different regions and the total surface area between females and males. Anthropometric measurements The ICC for the anthropometric measurements is presented in Table 3. The median of the ICC for the anthropometric measurements was 0.91. The resulting ICC was in the good or excellent range except for two measurements. The
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