Nine de Planque

Chapter 1 General introduction	9
Chapter 2 Using perfusion contrast for spatial normalization of ASL MRI images in a pediatric craniosynostosis population	31
Chapter 3 Cerebral blood flow of the frontal lobe in untreated children with trigonocephaly vs healthy controls - an arterial spin labeling study	49
Chapter 4 Reply: discussion cerebral blood flow of the frontal lobe in untreated children with trigonocephaly versus healthy controls: an arterial spin labeling study	63
Chapter 5 A diffusion tensor imaging analysis of frontal lobe white matter microstructure in trigonocephaly patients	69
Chapter 6 A diffusion tensor imaging analysis of white matter microstructures in non-operated craniosynostosis patients	91
Chapter 7 Cortical thickness in Crouzon-Pfeiffer syndrome: findings in relation to primary cranial vault expansion	109
Chapter 8 The course and interaction of ventriculomegaly and cerebellar tonsillar herniation in Crouzon syndrome over	129
Chapter 9 Clinical signs, interventions, and outcomes of three different treatment protocols in patients with Crouzon syndrome and acanthosis nigricans	149
Chapter 10 General discussion	165
Chapter 11 Summary	179
Chapter 12 Nederlandse samenvatting	185
Appendices List of publications	191
PhD portfolio	194
Curriculum vitae	196
Dankwoord	198

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