Contents Part I Chapter 1 General introduction 13 Chapter 2 Management of chronic anal fissure, results of a national survey among gastrointestinal surgeons in the Netherlands 39 International Journal of Colorectal disease 2022 Chapter 3 Pelvic floor physical therapy for pelvic floor hypertonicity: a systematic review of treatment efficacy 55 Sexual Medicine Reviews 2022 Chapter 4 To what extent are anorectal function tests comparable? A study comparing digital rectal examination, anal electromyography, 3-dimensional high resolution anal manometry and transperineal ultrasound 93 International Journal of Colorectal disease 2023 Part II Chapter 5 Pelvic floor physical therapy in the treatment of chronic anal fissure (PAF-study): study protocol for a randomized controlled trial 123 Contemporary Clinical Trials Communications 2021 Chapter 6 Pelvic floor physical therapy in patients with chronic anal fissure: a randomized controlled trial 145 Techniques in Coloproctology 2022 Reply to: Pelvic floor dysfunction and chronic anal fissure, a dog chasing its tail 167 Techniques in Coloproctology 2022 Chapter 7 Pelvic floor physical therapy in the treatment of chronic anal fissure (PAF-trial): quality of life outcome 171 Techniques in Coloproctology 2023 Chapter 8 Pelvic floor physical therapy in patients with chronic anal fissure: long term follow-up of a randomized controlled trial 189 International Journal of Colorectal disease 2023
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