Chapter 3 66 follow-up of three months. Only 1 RCT52 was unable to show a decrease in pelvic/ bladder discomfort and/or pain after PFPT compared to controls who received full body global therapeutic massage. One prospective study50 in women with IC, found a significant decrease in pelvic pain measured with Likert scores compared to baseline. The second prospective cohort study,45 in women with PVD demonstrated significant reduce of pain in the superficial pelvic floor muscles to a painful pressure stimulus induced with a vulvalgesiometer. Vulvar pain intensity ratings were also significantly decreased after treatment and no longer differed from non-affected controls. The third prospective study,47 in men with CPPS, found significantly lower pelvic pain-scores after PFPT measured with VAS. The fourth prospective study44 in men with CP/CPPS found a significant decrease in the subdomain pain of the National Institutes of HealthChronic Prostatitis Symptom Index (NIH-CPSI) after PFPT. The fifth prospective study49 in men with CP/CPPS also found significant improvement in pain from pre- to post-treatment in the subdomain of the NIH-CPSI and Pelvic Pain Symptom Scale (PPSS). Finally, the case study35 demonstrated a more than 25% reduction in pelvic pain symptom scores using VAS-scores. Sexual function Sexual function was investigated in all 4 RCTs,46,48,51,52 in one prospective study49 and the case study.35 One RCT51 found significantly higher post-treatment Female Sexual Function Index (FSFI) total scores for women in the IC/PBS patient group compared to pre-treatment, no significant differences were found relative to control. In men with CP/CPSS, no significant differences in sexual function were found from pre-to post-treatment and relative to controls using the Sexual Health Inventory for Men. In the second RCT52 no significant changes in FSFI total scores were observed from preto post-treatment, the same was true for controls. In the third RCT46 in women with dyspareunia, the FSFI total scores were significantly improved after PFPT compared to no treatment controls. In the fourth RCT48 in women with dyspareunia, the FSFIscores improved significantly from pre-to post-treatment, FSFI-lubrication and pain improved significantly compared to controls. Cervantes QoL-sexuality improved significantly from pre-to post-treatment but not compared to controls. The prospective study49 found significant improvement in sexual function measured with the sexual health domain of the PPSS. The case study35 demonstrated an improvement in sexual function measured with PPSS of more than 50% in 51% of the patients after PFPT.
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