10 Chapter 1 Overall, 5-year survival for oral cancer (OC) patients lies between 50% and 70% depending on the subsite (Figure 2) (6). Additionally, it varies depending on: disease stage at the time of diagnosis (7), sex, race/ethnicity, and age (Figure 2) (6, 8). Frequently, OCs are diagnosed at an early stage, as patient’s observe the tumor mass and experience symptoms that interfere with eating, speaking. Risk factors associated with environmental carcinogenesis, such as tobacco, alcohol, areca nut, betel quid, and poor dentition, should increase clinical suspicion for OSCC (9, 10). Figure 2: Ten-year relative survival for oral cancer patients per subsite and disease stage according to the Surveillance, Epidemiology, and End Results Program (6).
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