148 Chapter 5 Figure 2: Box plots illustrating statistically significant differences/similarities between the medians of the scores of inverse staining patterns observed for D1C2 and NCH-38 indicative for EMT and statistically significant differences between the medians of the scores of corresponding staining patterns observed for D1C2 and A2H2-3 indicative for MET ECD shedding according to the Median Test (n=203). Statistical significance was set at P<0.05. A. The median for uniform negativity observed using D1C2 (15.0%) is significantly higher than that observed for uniform positivity of NCH-38 (0.00%), implying that C-terminal MET immunoreactivity is generally lower than E-cadherin
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