76 Chapter 3 Supplementary figures Supplementary figure S1: Supplementary figures concerning MET immunoreactivity and antibody validation. A through C. immunoreactivity across the MET antibody validation cell line panel under reducing conditions observed with SP44 (A), C-12 (B) and C-28 (C).The immunoblots generated with SP44 and C-12 show MET specific as well as nonspecific protein bands. The MET specific protein bands are labelled on the left of each immunoblot. The MET nonspecific protein bands are labelled on the right of each immunoblot. For further information concerning the MET specific protein bands, the reader is referred to Supplementary table 2. The immunoblot generated with C-28 was found too poor to evaluate. D. images representing membranous, cytoplasmic and nuclear staining intensities. E. images representing percentages of MET positive cancer cells – membranous staining intensities 2-3 – observed with D1C2 across tissue cores sampled on the TMA. F. & G. Bland and Altman plots
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