138 Chapter 4 Supplemental table 1: Echocardiographic parameters’ descriptives per age decade IVSd in men (cm) Fabry men Healthy men Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 9 0.9 (0.9-1.2) 16 0.9 (0.8-1.0) 0.7 30-39 8 1.2 (1.1-1.2) 14 0.9 (0.8-1.0) 0.02* 40-49 4 1.3 (1.2-1.5) 14 1.0 (0.9-1.1) 0.06 50-59 8 1.8 (1.6-1.9) 15 1.0 (0.9-1.2) 0.001** 60-69 4 1.5 (1.5-1.7) 14 1.1 (1.0-1.2) 0.02* 70+ - - - - - RWT in men (-) Fabry men Healthy men Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 9 0.40 (0.38-0.41) 16 0.36 (0.34-0.38) 0.9 30-39 8 0.49 (0.43-0.61) 14 0.37 (0.33-0.42) 0.003** 40-49 4 0.54 (0.53-0.61) 11 0.37 (0.35-0.41) 0.007** 50-59 8 0.75 (0.65-0.78) 14 0.39 (0.35-0.47) 0.001** 60-69 4 0.56 (0.52-0.69) 14 0.42 (0.38-0.50) 0.1 70+ - - - - - LVMi in men (g/m2) Fabry men Healthy men Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 9 94 (70-102) 16 70 (63-79) 0.2 30-39 8 94 (90-112) 14 67 (59-75) 0.006** 40-49 4 120 (93-155) 11 65 (60-72) 0.007** 50-59 8 200 (177-267) 14 69 (67-80) <0.001*** 60-69 4 203 (162-244) 14 73 (64-78) 0.003** 70+ - - - - - LAVI in men (ml/m2) Fabry men Healthy men Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 9 30 (21-36) 15 26 (23-30) 1.0 30-39 9 28 (23-30) 14 27 (23-34) 1.0 40-49 4 40 (32-47) 13 27 (21-29) 0.8 50-59 8 52 (40-76) 14 30 (25-33) 0.01* 60-69 4 56 (43-69) 12 25 (23-28) 0.9 70+ - - - - - E/e’ in men (-) Fabry men Healthy men Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 9 8 (7-9) 16 6 (6-7) 0.02* 30-39 9 11 (8-11) 14 8 (7-8) 0.3 40-49 4 13 (12-14) 14 6 (6-7) 0.007** 50-59 8 17 (14-36) 14 8 (7-8) <0.001*** 60-69 4 21 (17-26) 14 9 (7-9) 0.01* 70+ - - - - - *p<0.05, ** p<0.01, ***p<0.001
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