139 Echocardiographic changes in Fabry disease IVSd in women (cm) Fabry women Healthy women Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 7 0.9 (0.8-0.9) 16 0.8 (0.7-0.8) 0.04* 30-39 9 0.9 (0.9-1.1) 14 0.8 (0.7-0.8) 0.2 40-49 5 1.0 (0.9-1.2) 14 0.8 (0.8-0.9) 0.3 50-59 16 1.3 (1.1-1.6) 16 0.9 (0.8-1.0) <0.001*** 60-69 15 1.4 (1.2-1.6) 13 1.0 (0.9-1.2) 0.02* 70+ 6 1.4 (1.3-1.7) 1 1.1 (-) 1.0 RWT in women (-) Fabry women Healthy women Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 7 0.36 (0.35-0.38) 16 0.34 (0.32-0.35) 0.4 30-39 9 0.40 (0.34-0.45) 14 0.33 (0.31-0.33) 0.03* 40-49 5 0.44 (0.44-0.52) 14 0.37 (0.33-0.41) 0.4 50-59 16 0.57 (0.45-0.76) 14 0.36 (0.33-0.40) <0.001*** 60-69 15 0.57 (0.46-0.63) 13 0.41 (0.37-0.51) 0.04* 70+ 6 0.57 (0.47-0.76) 1 0.45 (-) 1.0 LVMi in women (g/m2) Fabry women Healthy women Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 7 71 (69-75) 16 63 (56-68) 0.06 30-39 9 70 (60-93) 14 63 (51-73) 1.0 40-49 5 82 (79-106) 14 65 (55-71) 0.03* 50-59 16 113 (94-131) 14 62 (58-68) <0.001*** 60-69 15 129 (95-165) 13 71 (66-78) <0.001*** 70+ 6 136 (128-143) 1 63 (-) 1.0 LAVI in women (ml/m2) Fabry women Healthy women Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 6 23 (18-27) 16 28 (26-30) 0.8 30-39 9 25 (21-32) 12 29 (24-32) 1.0 40-49 5 27 (23-29) 11 33 (22-38) 1.0 50-59 15 34 (25-41) 15 28 (26-33) 1.0 60-69 14 38 (28-45) 13 33 (24-38) 1.0 70+ 5 63 (35-66) 1 26 (-) 1.0 E/e’ in women (-) Fabry women Healthy women Age category Number of observations Result (IQR) Number of observations Result (IQR) P- value 18-29 7 8 (7-9) 15 6 (6-8) 0.1 30-39 9 8 (7-10) 14 7 (6-8) 0.6 40-49 5 8 (7-12) 13 7 (7-8) 1.0 50-59 16 13 (11-16) 16 8 (7-10) 0.003** 60-69 15 14 (11-19) 13 9 (9-10) 0.01* 70+ 3 25 (18-28) 1 15 (-) 1.0 4
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