Mohamed El Sayed

143 Echocardiographic changes in Fabry disease Supplemental table 3A: other echocardiographic morphological and functional parameters’ descriptives (continued) E/A ratio in men (-) E/A ratio in women (-) Fabry men Healthy men Fabry women Healthy women Age category Number of observations Result Number of observations Result Age category Number of observations Result Number of observations Result 18-29 9 2.1 (1.5-2.1) 16 1.9 (1.7-2.2) 18-29 7 1.9 (1.8-2.0) 16 2.5 (2.0-2.9) 30-39 9 1.5 (1.3-1.7) 14 1.8 (1.6-2.2) 30-39 9 1.8 (1.6-2.2) 14 1.8 (1.5-2.1) 40-49 4 1.1 (0.9-1.2) 14 1.4 (1.3-1.7) 40-49 5 1.4 (1.2-1.4) 13 1.3 (1.2-1.4) 50-59 8 1.7 (1.0-2.7) 15 1.0 (0.9-1.3) 50-59 14 1.2 (0.9-1.3) 16 1.2 (1.1-1.5) 60-69 3 2.8 (2.0-3.0) 14 1.0 (0.8-1.1) 60-69 15 1.1 (0.8-1.4) 13 1.0 (0.7-1.2) 70+ - - - - 70+ 3 2.5 (1.6-3.9) 1 0.6 (-) GLS in men (%) GLS in women (%) Fabry men Healthy men Fabry women Healthy women Age category Number of observations Result Number of observations Result Age category Number of observations Result Number of observations Result 18-29 9 -18 (-17,-19) 15 -20 (-19, -21) 18-29 5 -21 (-21,-22) 16 -21 (-21, -22) 30-39 6 -17 (-16,-18) 14 -20 (-20, -22) 30-39 9 -22 (-20,-22) 14 -22 (-21, -24) 40-49 2 -15 (-16,-14) 14 -20 (-19, -21) 40-49 3 -18 (-17,-20) 12 -22 (-19, -23) 50-59 7 -9 (-8,-14) 14 -20 (-19, -22) 50-59 13 -17 (-20,-12) 16 -22 (-21, -23) 60-69 4 -13 (-11,-15) 12 -19 (-19, -21) 60-69 11 -17 (-13,-19) 13 -21 (-19, -22) 70+ - - - - 70+ 4 -13 (-11,-13) 1 -19 (-) Biplane LV EF in men (%) Biplane LV EF in women (%) Fabry men Healthy men Fabry women Healthy women Age category Number of observations Result Number of observations Result Age category Age category Number of observations Result Number of observations 18-29 9 54 (53-59) 15 61 (57-65) 18-29 6 56 (54-58) 16 59 (58-61) 30-39 7 58 (56-63) 14 60 (60-62) 30-39 9 64 (62-67) 14 64 (57-68) 40-49 4 59 (55-64) 14 59 (57-60) 40-49 4 57 (56-60) 13 60 (58-63) 50-59 7 52 (45-58) 14 60 (56-64) 50-59 14 67 (65-71) 16 64 (61-67) 60-69 4 55 (50-56) 13 55 (55-59) 60-69 14 57 (56-64) 13 61 (58-62) 70+ - - - - 70+ 6 54 (49-61) 1 65 (-) 4

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