145 Echocardiographic changes in Fabry disease Supplemental table 3B: Other echocardiographic morphological and functional parameters’ descriptives, that are only available in FD patients Aortic root diameter- Valsalva (cm) Fabry men Fabry women Age category Number of observations Result Age category Number of observations Result 18-29 9 3.7 (3.5-3.8) 18-29 7 2.8 (2.7-3.0) 30-39 9 4.2 (3.7-4.2) 30-39 9 2.9 (2.7-3.2) 40-49 4 4.1 (3.8-4.5) 40-49 5 2.7 (2.6-2.9) 50-59 8 4.1 (3.8-4.4) 50-59 16 3.5 (3.1-3.8) 60-69 4 3.8 (3.8-4.0) 60-69 15 3.1 (2.9-3.2) 70+ - - 70+ 6 3.5 (3.2-3.6) TR Vmax (cm/s) Fabry men Fabry women Age category Number of observations Result Age category Number of observations Result 18-29 9 2.2 (2.2-2.4) 18-29 5 2.3 (2.1-2.3) 30-39 7 2.1 (2.1-2.4) 30-39 7 2.3 (2.1-2.3) 40-49 4 2.2 (2.2-2.4) 40-49 4 2.4 (1.9-2.7) 50-59 4 2.2 (2.1-2.3) 50-59 12 2.3 (2.2-2.6) 60-69 4 2.6 (2.5-2.7) 60-69 10 2.5 (2.4-2.7) 70+ - - 70+ 6 2.5 (2.3-2.6) Results are displayed as median with its Interquartile range (IQR) Supplemental table 4: Effect of the echocardiographic parameters on the first obtained echocardiogram on Atrial fibrillation during follow-up in FD patients based on a Cox proportional hazard model Echocardiographic parameter β HR- Atrial fibrillation (exp(β)) 95% CI- p value IVSd 0.27 1.31 1.15-1.49 (0.00005)*** RWT 0.41 1.50 1.25-1.80 (0.00001)*** LVMi 0.02 1.02 1.01-1.03 (0.0004)*** LAVI 0.08 1.08 1.04-1.12 (0.0003)*** E/e’ 0.18 1.20 1.10-1.32 (0.0001)*** *p<0.05, ** p<0.01, ***p<0.001 4
RkJQdWJsaXNoZXIy MTk4NDMw