Mohamed El Sayed

203 Summary and general discussion 37. Rob, D., et al., Heart failure in Fabry disease revisited: application of current heart failure guidelines and recommendations. ESC Heart Fail, 2022. 38. Pieske, B., et al., How to diagnose heart failure with preserved ejection fraction: the HFA- PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur Heart J, 2019. 40(40): p. 3297-3317. 39. Voors, A.A., et al., The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial. Nat Med, 2022. 28(3): p. 568-574. 40. McDonagh, T.A., et al., 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J, 2021. 42(36): p. 3599-3726. 41. Lobo, T., et al., Cardiovascular testing in Fabry disease: exercise capacity reduction, chronotropic incompetence and improved anaerobic threshold after enzyme replacement. Intern Med J, 2008. 38(6): p. 407-14.1. 42. Franzen, D.P., et al., Long-term follow-up of pulmonary function in Fabry disease: A bi-center observational study. PLOS ONE, 2017. 12(7): p. e0180437. 43. Koskenvuo, J.W., et al., Cardiopulmonary involvement in Fabry’s disease. Acta Cardiol, 2010. 65(2): p. 185-92. 44. Chimenti, C., et al., Cardiac and skeletal myopathy in Fabry disease: a clinicopathologic correlative study. Human pathology, 2012. 43(9): p. 1444-1452. 45. de la Mata, M., et al., Mitochondrial Dysfunction in Lysosomal Storage Disorders. Diseases, 2016. 4(4). 46. Platt, F.M., B. Boland, and A.C. van der Spoel, The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction. J Cell Biol, 2012. 199(5): p. 723-34. 47. Riley, M.S., D.P. Nicholls, and C.B. Cooper, Cardiopulmonary Exercise Testing and Metabolic Myopathies. Ann Am Thorac Soc, 2017. 14(Supplement_1): p. S129-s139. 48. Whipp, B.J., et al., Parameters of ventilatory and gas exchange dynamics during exercise. J Appl Physiol Respir Environ Exerc Physiol, 1982. 52(6): p. 1506-13. 6

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