27 Cardiac outcomes in Fabry disease Methods Patient and public involvement This is an observational longitudinal retrospective study, using data from all adult patients with a definite diagnosis of FD (figure 1) that have been under follow-up at any time at the Amsterdam University Medical Centers (AUMC), the national referral center for FD patients in the Netherlands. Figure 1: Flowchart for the diagnosis and phenotype allocation in Fabry disease. 2
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