35 Cardiac outcomes in Fabry disease for CR analysis). Having a classical phenotype and being male significantly increased the risk of MACE (table 3). Hazard ratio (HR) for MACE in men with a classical versus non-classical phenotype was 6.1 and in men versus women with a classical disease phenotype 5.0 (table 4). Of the patients who developed MACE, MI was the first recorded event in 47% of men with classical FD, 64% of women with classical FD, and 57% of men with non-classical FD. Excluding MI from the MACE analysis, did not change the observed differences between the patient groups (see supplemental results). 2
RkJQdWJsaXNoZXIy MTk4NDMw