52 Chapter 2 Supplemental table 2: Prevalence, event rates and age at onset of individual outcomes † (continued) All (213) Men (83) Women (130) Classical (57) Non-classical (26) Classical (98) Non-classical (32) 12. Systolic dysfunction on MRI or echocardiography Number of patients 28 (13%) 11 (19%) 8 (31%) 8 (8%) 1 (3%) Event rate, with 95%-CI 3.9 (2.7-5.6) 7.1 (3.7-12.4) 6.7 (3.1-12.8) 2.5 (1.2-4.7) 0.9 (0.04-4.3) Age at first documentation 60 (29-77) 52 (29-64) 64 (53-69) 65 (54-77) 72 (-) 13. Left ventricular outflow tract obstruction Number of patients 8 (4%) 2 (4%) 1 (4%) 4 (4%) 1 (3%) Event rate, with 95%-CI 1.1 (0.5-2.1) 1.3 (0.2-4.3) 0.8 (0.04-4.1) 1.2 (0.4-3.0) 0.9 (0.04-4.3) Age at first documentation 56 (31-65) 43 (31-55) 58 (-) 57 (46-61) 65 (-) 14. Moderate or severe heart valve disease Number of patients 39 (18%) 14 (25%) 6 (23%) 16 (16%) 3 (9%) Event rate, with 95%-CI 5.5 (4.0-7.4) 9.1 (5.2-14.8) 5.0 (2.0-10.5) 5.0 (3.0-7.9) 2.6 (0.7-7.2) Age at first documentation 58 (36-77) 51 (36-61) 65 (51-70) 61 (47-77) 74 (65-76) 15. Heart surgery/ intervention* Number of patients 10 (5%) 2 (4%) 3 (12%) 5 (5 %) 0 (0%) Event rate, with 95%-CI 1.4 (0.7-2.5) 1.3 (0.2-4.3) 2.5 (0.6-6.9) 1.6 (0.6-3.5) 0 (-) Age at first surgery/ intervention 63 (49-72) 53 (49-57) 64 (64-68) 61 (52-72) (-) Data are presented as number (percentage) or median (range). All event rates are per 1000 patient years from age 15 onwards. † Events per 1000 person years from age of 15 = (Number of events/ Cumulative follow up from age 15)x1000 * heart surgery or intervention other than percutaneous coronary intervention or coronary artery bypass graft surgery AV = atrioventricular; CRT = cardiac resynchronization therapy; ICD = implantable cardiac defibrillator; PM = pacemaker
RkJQdWJsaXNoZXIy MTk4NDMw