92 Chapter 3 Supplemental table 2: ECG descriptives per age decade (the last available ECG per FD patient per decade was selected to ensure that the influence of repeated measurements was limited) P-wave duration in men (ms) Age category Available ECGs in Fabry men, n Fabry men Median (IQR) Available ECGs in Controls- men, n Controls- men Median (IQR) P- value 18-29 25 110 (102-118) 262 108 (102-116) 1.0 30-39 13 120 (108-122) 379 112 (106-118) 0.2 40-49 15 126 (120-128) 374 116 (110-122) 0.01* 50-59 9 128 (114-130) 409 118 (112-124) 1.0 60-69 1 150 (-) 235 121 (112-128) 0.4 70+ - - - - - PR-interval in men (ms) Age category Available ECGs in Fabry men, n Fabry men Median (IQR) Available ECGs in Controls- men, n Controls- men Median (IQR) P- value 18-29 25 146 (138-158) 262 156 (142-170) 0.6 30-39 13 152 (132-176) 379 158 (144-174) 1.0 40-49 15 144 (134-149) 374 162 (150-176) 0.02* 50-59 9 146 (132-162) 409 166 (152-178) 0.1 60-69 1 186 (-) 235 168 (152-188) 1.0 70+ - - - - - QRS-duration in men (ms) Age category Available ECGs in Fabry men, n Fabry men Median (IQR) Available ECGs in Controls- men, n Controls- men Median (IQR) P- value 18-29 25 104 (94-108) 262 102 (96-108) 1.0 30-39 13 102 (96-114) 379 102 (96-108) 1.0 40-49 18 113 (105-137) 374 102 (96-106) <0.001*** 50-59 15 134 (121-149) 415 100 (94-106) <0.001*** 60-69 3 166 (159-184) 237 100 (94-106) 0.02* 70+ - - - - - QTc in men (ms) Age category Available ECGs in Fabry men, n Fabry men Median (IQR) Available ECGs in Controls- men, n Controls- men Median (IQR) P- value 18-29 25 388 (373-398) 262 405 (387-418) 0.02* 30-39 13 414 (410-431) 379 407 (394-422) 0.3 40-49 18 428 (420-452) 374 411 (396-424) 0.001** 50-59 15 438 (414-478) 415 416 (402-430) 0.02* 60-69 3 492 (475-517) 237 422 (405-436) 0.02* 70+ - - - - -
RkJQdWJsaXNoZXIy MTk4NDMw