Mohamed El Sayed

Chapter 1 General introduction and thesis outline	9
Chapter 2 Influence of sex and phenotype on cardiac outcomes in patients with Fabry disease	23
Chapter 3 ECG Changes During Adult Life in Fabry Disease: Results from a Large Longitudinal Cohort Study	61
Chapter 4 Early echocardiography markers of Fabry cardiomyopathy identified in a multi-decade longitudinal cohort study	111
Chapter 5 Early risk stratification for natural disease course in Fabry patients using plasma globotriaosylsphingosine levels	155
Chapter 6 Summary and general discussion	183
Appendices	205
Dutch summary (Nederlandse samenvatting)	206
Arabic summary	210
Contributing authors’ affiliations	213
Portfolio	215
Curriculum vitae	217
Dankwoord	218

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