Wouter Woud

Extracellular Vesicles are Associated with Human Donor Kidney Characteristics 5 133 Kidney ID K1 # K2 # K3 K4 K5 K6 K7 ## K8 ## Renal Blood Flow (mL/minute/100gr) T60 16,54 84,66 83,02 12,14 30,54 23,38 16,58 25,82 T180 31,20 84,66 93,37 25,63 36,24 35,71 24,39 31,92 T360 45,11 91,48 151,19 30,44 47,99 66,23 58,54 92,96 Intrarenal Vascular Resistance (mmHg/mL/minute) T60 1,7 0,25 0,24 1,19 0,82 1,04 1,1 1,36 T180 0,9 0,25 0,21 0,56 0,69 0,68 0,75 1,10 T360 0,63 0,23 0,13 0,47 0,52 0,37 0,31 0,38 Total Urine Production (mL) – Accumulated T60 0 71,5 63 0 0 0 0 0 T180 0 100,5 120 0 3 12 0 0 T360 0 116 303 0 3 48 0 0 Transplantability assessment post NMP No No Yes No Yes No No No Table 2 – NMP viability characteristics as measured at 60 / 180 / 360 minutes of NMP. After 6 hours of NMP, each ECD kidney was judged by an independent transplant surgeon and nephorologist whether or not the organ was deemed suitable for transplantation (transplantability assessment). # and ## represent paired kidney grafts from same donor.

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