Chapter 5 134 Figure 4 – Correlation analysis of concentrations of released EV subsets with donor kidney and NMP viability characteristics. Overview of the EV subsets for which statistically significant correlations were obtained. Analysis of A) correlation between CD9 single-positive, B) CFSE and CD9 double-positive, and C) CFSE and CD63 double-positive EVs with CIT. D) Analysis of correlation between CD81 and CD45 double-positive EVs with donor age. Most notably, correlation analysis of CD31 single-positive EVs with E) renal flow and F) intrarenal vascular resistance showed inverse correlations. EV concentrations as excreted by each ECD kidney are represented by shape, with open triangles representing K3 and K5 (which were deemed transplantable post NMP – Table 2). # and ## represent paired kidney grafts from same donor.
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