120 Chapter 10 Results Exploratory pilot study Clinicopathological characteristics In the pilot study from a total of 33 patients, 74 histological sections of 40 tumors were analyzed. The clinicopathological characteristics of the patients are presented in table 1. A total of 7 patients had 2 tumors; in 4 of them located in 2 separated wedge excisions, 1 in a lobectomy and a wedge excision and 2 patients with a double tumor in 1 lobe. The histological diagnosis was invasive carcinoma for most tumors, except for 3 with a diagnosis of adenocarcinoma in-situ, of which 1 was in combination with a separate invasive carcinoma. Table 1. Clinicopathological variables of pilot study patients. n (%) Age (mean – SD) 63 (10) Sex Male 14 (42%) Female 19 (58%) Previous malignancy Squamous cell carcinoma larynx 2 (6%) Adenocarcinoma sigmoid 1 (3%) Mantel cell lymphoma 1 (3%) None 29 (88%) Surgery procedure Lobectomy 23 (70%) Bilobectomy 1 (3%) Wedge resections (n=12)a 8 (24%) Lobectomy and wedge 1 (3%) Pathological stage 1 11 (33%) 2 10 (30%) 3 10 (30%) 4 2 (6%) Histological diagnosis (patients) AIS 2 (6%) Invasive 31 (94%)
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