133 Editorial (PRO/) CON: is STAS an inducible artifact? Figure 1. A: Grossing knife on the left side and the thickness of the blade holder in the caliper on the right side (arrow head). B: The relative size of blade holder (blue) and blade (orange) compared to ‘loose tumour fragment’ in peripheral lung tissue. During cutting a prominent force is applied on the section. An unsolved question will be whether the jagged or ragged edges are caused by the knife itself or by the force during cutting. The “jagged” or “ragged” description is at a macroscopic level appealing, like an imaginary cut in a finger, but is at microscopic level taking the broad blade into account only understandable if sheared cutting forces tear clusters apart. 11
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