58 Chapter 4 Figure 4. Kaplan-Meier survival curves showing overall survival and a better prognosis in adenocarcinoma (AdC) (blue) than squamous cell carcinoma (SqCC) (red) in the second nodule subtype (p=0.004), but not in the other three subtypes. Table 4. Mean 5-Year OS of T3N0 NSCLC and stage IIA and IIIA as in the IASLC Database for the TNM-7 and TNM-8 with comparison to our study, Including histologic subtypes and CIs. TNM-7 Proposed TNM-8 Current study stage 5 yrs OS stage 5 yrs OS 5 yrs OS 95% CI IIA 57% IIA 65% All pT3N IIB 49% IIB 56% 47.9% 43.5%-52.2% All >7cm IIB 49% IIIA 41% 47.2% 39.9%-54.5% AdC n.a. n.a. 43.0% 31.0%-55.1% SqCC n.a. n.a. 51.7% 40.2%-63.3% All 2nd tumor IIB 49% IIB 49% 62.8% 54.2%-71.3% AdC n.a. n.a. 65.1% 52.9%-77.4% SqCC n.a. n.a. 47.2% 31.8%-62.6% All parietal pleural invasion IIB 49% IIB 49% 45.3% 36.8%-53.7% AdC n.a. n.a. 49.0% 36.5%-61.5% SqCC n.a. n.a. 45.4% 32.5%-58.2%
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