87 A Prospective Study of Loose Tissue Fragments in resected NSCLC Figure 2. Tissue section showing AdC on the left side. The tumor border is marked with thick black line. Loose fragments at a distance more than 1 high power field (0.5mm) from the tumor border (thin black line) are scored as loose fragments (arrows; hematoxylin and eosin staining, eg, block 3 of Fig. 1). Benign and malignant loose fragments were separately noted. All loose fragments in one field of view in x10 objective count as one occurrence, independent of the actual number of loose fragments in that microscopic field. The total count of loose fragments in each block was estimated by counting all positive x10 objective fields. Statistics The total count of loose fragments in each block was compared by the Friedman test for repeated measures because of non-normality of the number of loose fragments. Post hoc analysis, comparing blocks 2 to 4 with block 1 separately, was performed with the Wilcoxon signed rank test and corrected for multiple testing by the Bonferroni correction. Differences between groups in number of loose fragments between different blocks were compared using the Mann-Whitney U test. Statistical analyses were carried out by SPSS for Windows and Mac version 18.0. (IBM, New York, NY). 6
RkJQdWJsaXNoZXIy MTk4NDMw