Annelienke van Hulst

140 Chapter 4 Supplemental Table 2. Univariable logistic regression analyses dexamethasone-induced neurobehavioral problems No dexamethasone-induced neurobehavioral problems (ΔSDQ<5) Median (IQR) or n (%) Patient demographics n = 35 Age, years 5.8 (4.3-13.1) Sex Boy 23 (65.7) Girl 12 (34.3) T1 SDQ Total Difficulties score 6 (2-14) T1 SDSC Total score 37 (32-46) Disease and treatment characteristics n = 35 Week maintenance 37 (27-43) Asparaginase during study No 32 (91.4) Yes 3 (8.6) Type ALL1 B-cell ALL 30 (85.7) T-cell ALL 4 (11.4) CNS involvement2 No 27 (77.1) Yes 8 (22.9) Family characteristics n = 32 Age mother 38 (36-44) Age father 42 (38-46) Who completed questionnaires Mother 25 (71.4) Father 10 (28.6) Nationality mother3 Dutch 24 (75) Other 8 (25) Nationality father Dutch 24 (77.4) Other 7 (22.6) Level of education mother Low/middle 11 (35.5) High 20 (64.5) Level of education father Low/middle 15 (50.0) High 15 (50.0) Number of siblings 1 (1-2) NOSI-K n = 32 NOSI-K T1 37 (28-52) NOSI-K T2 41 (31-49) NOSI-K delta (T2-T1)4 0.5 (-3-6)

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