Annelienke van Hulst

146 Chapter 4 Supplemental Table 3. Univariable logistic regression analyses dexamethasone-induced sleep problems No dexamethasone-induced sleep problems (ΔSDSC<7) Median (IQR) or n (%) Patient demographics n = 43 Age 5.5 (4.0-9.8) Sex Boy 28 (65.1) Girl 15 (34.9) T1 SDSC Total score 38 (33-50) T1 SDQ Total Difficulties score 7 (2-13) Disease and treatment characteristics n = 43 Week maintenance 33 (22-43) Asparaginase during study No 37 (86.0) Yes 6 (14.0) Type ALL1 B-cell ALL 39 (90.7) T-cell ALL 3 (7.0) CNS involvement2 No 35 (81.4) Yes 8 (18.6) Family characteristics n = 34 Age mother 38 (34-46) Age father 42 (36-47) Who completed questionnaires Mother 32 (74.4) Father 11 (25.6) Nationality mother Dutch 27 (79.4) Other 7 (20.6) Nationality father Dutch 26 (78.8) Other 7 (21.2) Level of education mother Low/middle 14 (42.4) High 19 (57.6) Level of education father Low/middle 15 (45.5) High 18 (54.5) Number of siblings 1 (1-2) NOSI-K n = 42 NOSI-K T1 43 (32-56) NOSI-K T2 46 (36-70) NOSI-K delta (T2-T1)3 1 (-2-19)

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