166 Chapter 5 Table 5. Estimated regression coefficients ( β) along with 95%-confidence interval (CI) from a multivariable linear regression models for delta leptin (corrected for leptin T1) Patient characteristics Leptin SDS delta β 95%-Confidence Interval Lower bound Upper bound Age, years 0.08 0.02 0.15 Leptin T1 -0.60 -0.73 -0.47 Intercept 1.18 Sex Boy Girl -0.32 -0.78 0.14 Leptin T1 -0.49 -0.60 -0.38 Intercept 1.96 Fat mass T1 0.01 -0.03 0.40 Leptin T1 -0.48 -0.60 -0.35 Intercept 1.76 Fatigue SDS T1 0.07 -0.05 0.20 Leptin T1 -0.53 -0.65 -0.41 Intercept 1.82 SDSC total scoreT1 -0.01 -0.03 0.01 Leptin T1 -0.50 -0.61 -0.39 Intercept 2.25 Disease and treatment characteristics β 95%-Confidence Interval Lower bound Upper bound Week maintenance -0.02 -0.04 -0.01 Leptin T1 -0.50 -0.60 -0.40 Intercept 2.65 Asparaginase No Yes 1.09 0.39 1.79 Leptin T1 -0.47 -0.58 -0.37 Intercept 1.71 CNS involvement No Yes 0.29 -0.29 0.86 Leptin T1 -0.49 -0.60 -0.38 Intercept 1.77 Abbreviations: SDS: standardized deviation score, SE: standard error, 95%-CI: 95%-confidence interval, SDSC: sleep disturbance scale for children.
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