Annelienke van Hulst

211 Hydrocortisone as an intervention (RCT) 6 Supplemental table 6. Continued Least extreme hunger feeling Estimated effect 95% CI Lower bound Upper bound Intervention - Placebo - Hydrocortisone 0.63 -1.87 3.14 Start group - Placebo - Hydrocortisone 0.26 -0.89 1.41 Week of maintenance treatment 0.003 -0.05 0.05 Interaction intervention and week of maintenance treatment - Placebo - Hydrocortisone -0.03 -0.08 0.03 Sex 0.08 -1.06 1.22 Asparaginase -0.53 -2.65 1.59 Age at registration -0.21 -0.39 -0.29 Parent who completed questionnaire -0.61 -1.65 0.44 Hunger feeling in the morning (fasting) Estimated effect 95% CI Lower bound Upper bound Intervention - Placebo - Hydrocortisone 2.74 0.07 5.41 Start group - Placebo - Hydrocortisone -0.42 -1.93 1.09 Week of maintenance treatment 0.02 -0.04 0.08 Interaction intervention and week of maintenance treatment - Placebo - Hydrocortisone -0.06 -0.12 0.005 Sex -1.18 -2.68 0.33 Asparaginase 0.13 -2.62 2.89 Age at registration -0.05 -0.29 0.19 Parent who completed questionnaire -0.09 -1.38 1.20

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