Annelienke van Hulst

213 Hydrocortisone as an intervention (RCT) 6 Supplemental table 7. Continued Emotional functioning Estimated effect 95% CI Lower bound Upper bound Intervention - Placebo - Hydrocortisone -0.10 -22.22 22.02 Start group - Placebo - Hydrocortisone -6.04 -14.51 2.43 Week of maintenance treatment 0.23 -0.16 0.63 Interaction intervention and week of maintenance treatment - Placebo - Hydrocortisone -0.09 -0.60 0.41 Sex -4.90 -13.36 3.56 Asparaginase -1.48 -17.40 14.44 Age at registration -0.13 -1.46 1.21 Parent who completed questionnaire 5.62 -1.97 13.22 Social functioning Estimated effect 95% CI Lower bound Upper bound Intervention - Placebo - Hydrocortisone 0.86 -16.31 18.03 Start group - Placebo - Hydrocortisone -1.75 -9.79 6.29 Week of maintenance treatment 0.07 -0.29 0.42 Interaction intervention and week of maintenance treatment - Placebo - Hydrocortisone -0.03 -0.42 0.36 Sex 2.39 -5.70 10.47 Asparaginase 1.77 -13.21 16.74 Age at registration -0.35 -1.63 0.93 Parent who completed questionnaire 3.13 -3.66 9.91

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