Annelienke van Hulst

215 Hydrocortisone as an intervention (RCT) 6 Supplemental table 8. Repeated measurement of Δ Distress Thermometer for parents in the RCT (T3-T10) Thermometer Score Estimated effect 95% CI Lower bound Upper bound Intervention - Placebo - Hydrocortisone 0.62 -2.23 3.46 Start group - Placebo - Hydrocortisone 0.76 -0.47 1.98 Week of maintenance treatment -0.03 -0.09 0.02 Interaction intervention and week of maintenance treatment - Placebo - Hydrocortisone -0.01 -0.08 0.05 Sex 0.77 -0.46 2.00 Asparaginase -1.14 -3.43 1.16 Age at registration -0.06 -0.25 0.14 Parent who completed questionnaire 0.03 -1.03 1.10

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