242 Chapter 7 SUPPLEMENTAL TABLES Supplemental Table 1. Patients’ characteristics for prednisone response Poor prednisone response n = 14 Good prednisone response n = 114 Sex n (%) Girl 5 (35.7) 44 (38.6) Boy 9 (64.3) 70 (61.4) NCI risk group n (%) Standard risk 4 (28.6) 66 (57.9) High risk 9 (64.3) 48 (42.1) NR3C1 n (%) Low 13 (92.9) 49 (43.0) High 1 (7.1) 65 (57.0) NR3C2 n (%) Low 11 (78.6) 52 (45.6) High 3 (21.4) 62 (54.4) NCI-risk category: standard risk= <10 years and white cell count at diagnosis <50x109/L, high risk= other Abbreviations: n: number, NCI: National Cancer Institute Supplemental Table 2. Estimated odds ratio (OR) with 95%-CI for prednisone response Poor prednisone response OR (MVA) 95%-CI Sex n (%) Girl Boy 0.922 0.262-3.244 NCI risk group n (%) Standard risk High risk 3.221 0.893-11.622 NR3C1 n (%) Low High 0.060 0.007-0.481 Poor prednisone response OR (MVA) 95%-CI Sex n (%) Girl Boy 0.998 0.298-3.340 NCI risk group n (%) Standard risk High risk 3.257 0.943-11.245 NR3C2 n (%) Low High 0.240 0.062-0.923 Odds ratio’s (OR) for either GR (NR3C1) or MR (NR3C2) on prednisone response are depicted, corrected for sex and NCI risk group (multivariable regression analysis). Due to low number of patients with poor prednisone response, interpretation of the OR is not possible. NCI-risk category: standard risk= <10 years and white cell count at diagnosis <50x109/L, high risk= other Abbreviations: n: number, CI: confidence interval, NCI: National Cancer Institute, OR: odds ratio, MVA: multivariable analysis
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