81 Risk factors: a systematic review 2 Studied no of SNPs (adj for multiple testing) Gene/ region Variant Effect allele / genotype MVA adjust for: OR P-value 99 (no multiple testing) AHSG rs4918 GG vs CC+CG Not stated Not stated 0.023 (sleep duration) 0.005 (sleep time) IL-6 rs1800795 rs13447445 GG vs CG+CC CG vs CC NS NS Type of APR History Psychosis Schizophrenia (half-brother) Psychosis ADHD (self) Emotional and behavioral problems PDD-NOS (self) Tic disorder + ADHD (self) Psychosis Suicidal ideation (grandfather) Depression (mother) Behavior and mood symptoms Behavioral problems Mood problems Anxiety disorder, substance dependence (family) ASD (self), mood disorder (parent) Depression, anxiety, bipolar disorder (family) Mood disorder HFA and ADHD (self) Depression (mother) Panic Mania Mixed adjustment disorder (self), depression (mother), PTSD (father), depression (sibling). Dysthymia (mother), panic attacks (father), depression and mania (grandparents)
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