198 Chapter 6 Results Seventy-seven patients with OPSCC met the inclusion criteria and were included in this study. Extractions were performed in 66% of the OPSCC patients. The mean number of extracted teeth was 4.1 ± 5.6 per patient. During CRT/BRT, 40 patients (52%) experienced significant weight loss of more than 5%. Baseline characteristics are presented in Table 2. Patients with significant weight loss during CRT/BRT had a higher BMI at start of treatment compared to patients without significant weight loss. In addition, a higher proportion of patients with significant weight loss had teeth removed to clear them from potential sources of infection. Table 2 – Baseline characteristics Stable weight or less than 5% loss during CRT/BRT n = 37 (48%) >5% weight loss during CRT/BRT n = 40 (52%) p value Patient characteristics Age (years) mean ± SD 58.4 ± 9.5 59.4 ± 6.0 median (IQR) 60.0 (13) 59.5 (9) 0.971c Male 25 (68%) 29 (73%) 0.637d Female 12 (32%) 11 (28%) Smoking history 33 (89%) 35 (88%) 1.000a No history of smoking 4 (11%) 5 (13%) Alcohol consumption 19 (51%) 27 (68%) 0.149d No alcohol consumption 18 (49%) 13 (33%) BMI at start RT (kg/m2); mean ± SD 24.5 ± 5.0 26.7 ± 4.2 0.039b Percentage weight loss prior to CRT/BRT; mean ± SD 2.4 ± 3.7 1.7 ± 3.2 0.373b Dysphagia (CTCAE grade) 0 - No symptoms of dysphagia 18 (49%) 15 (38%) 0.077d 1 - Symptomatic, regular diet 7 (19%) 17 (43%) 2 - Symptomatic, altered eating/swallowing 12 (32%) 8 (20%)
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