Doke Buurman

200 Chapter 6 Table 2 – Continued Stable weight or less than 5% loss during CRT/BRT n = 37 (48%) >5% weight loss during CRT/BRT n = 40 (52%) p value Eichner Index A at first assessment 7 (19%) 12 (30%) 0.427d Eichner Index B at first assessment 11 (30%) 8 (20%) Eichner Index C at first assessment 19 (51%) 20 (50%) Eichner Index A at start RT 4 (11%) 8 (20%) 0.547a Eichner Index B at start RT 13 (35%) 11 (28%) Eichner Index C at start RT 20 (54%) 21 (53%) Decrease in Eichner Index (ABC) due to tooth extractions prior to CRT/BRT 4 (11%) 5 (13%) 1.000a No decrease in Eichner Index (ABC) due to tooth extractions prior to CRT/BRT 33 (89%) 35 (88%) OU at first assessment; mean ± SD 3.5 ± 4.5 4.0 ± 4.7 0.642b OU at start RT; mean ± SD 2.1 ± 3.6 3.2 ± 4.4 0.249b Loss of OU due to tooth extractions prior to CRT/BRT mean ± SD 1.4 ± 2.3 0.8 ± 1.8 median (IQR) 0.0 (3) 0.0 (1) 0.317c Tooth extractions prior to CRT/BRT 20 (54%) 31 (78%) 0.030d No tooth extractions prior to CRT/BRT 17 (46%) 9 (23%) Tooth extractions and/or additional interventions 23 (62%) 32 (80%) 0.083d No tooth extractions and/or additional interventions 14 (38%) 8 (20%) Number of removed teeth; mean ± SD 3.4 ± 5.0 4.8 ± 6.1 0.289b Treatment characteristics Primary CRT/BRT 35 (95%) 38 (95%) 1.000a Postoperative CRT 2 (5%) 2 (5%) Cisplatin 27 (73%) 29 (73%) 0.963d Cetuximab 10 (27%) 11 (28%)

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